Which agency is responsible for regulating the operation of two-way radios?

The Federal Communications Commission (FCC) is the agency responsible for regulating the operation of two-way radios. This agency oversees all forms of communication in the U.S., including television, radio, satellite, and telecommunications. Specifically, the FCC establishes rules and regulations related to the frequencies and licensing needed for operating two-way radio systems, ensuring that operators comply with policies designed to minimize interference between different communication services. Their role is critical in managing the radio spectrum to allow for effective and efficient use of frequencies, maintaining order within various communication sectors.

The other organizations listed have distinct roles that do not pertain specifically to two-way radio regulation. The Federal Emergency Management Agency (FEMA) is focused on emergency management and response, while the National Telecommunications and Information Administration (NTIA) is more concerned with federal government use of the spectrum and advising on telecommunications issues. "FCCB" does not represent a recognized agency related to this topic. Thus, it is clear that the FCC is the correct and relevant authority for regulating two-way radios.